Personal Introduction: Yanhui Lu, a doctoral supervisor.Her research primarily investigates the mechanisms linking gut microbiota to chronic diseases, alongside the roles of nutrition and clinical nursing within interdisciplinary domains. She has served as the project leader or key member for several national, provincial/ministerial, and university-level projects, including the integration project for major research plan of the National Natural Science Foundation of China, sub-projects of the key project by the Ministry of Science and Technology for “Stem Cell Research and Organ Repair”, youth project of National Natural Science Foundation of China, the first-class funding of Postdoctoral Foundation, youth project of Beijing Municipal Natural Science Foundation and Peking University’s Clinical Medicine X+ Youth Special Project, with total funding amounting to 4.34 million RMB. She has published over 30 SCI papers as the corresponding/first author in high-impact journals such as Nature Communications, Pharmacological Research, BMC Medicine, and has been granted one invention patent as the primary inventor. She currently serves as a member of the Special Nutrition Branch of the Chinese Nutrition Society, a member of the Nutrition and Immunology Branch of the Chinese Nutrition Society, an executive director of the Nursing Branch of the Chinese Health Management Association, the editor-in-chief of the Nursing Communication magazine, the review expert for Yunnan Province science and technology strategy and several other academic part-time positions. |
Personal profile (experiences such as Education, Employment, courses you are teaching): Education: 2018 -2021, Post-doctor, Nursing, Peking University 2014 -2017, Ph.D, Nutrition and Food Hygiene, Capital Medical University Employment: 2021-2022,Associate professorin the School of Nursing, Peking University 2008 -2014,Head nurse of ICU and Deputy Director of Nursing Department, Linyi Mental Health Center 2004 -2008, Nurse of Emergency Department and ICU, Linyi People’s Hospital Course teaching: Functional Assessment and Practice, Internal Medical Nursing, Emergency Nursing |
Selected projects (including title and fund support):
Integration project for major research plan of the National Natural Science Foundation of China, Study in the regulation and intervention strategies of gut microbiota in metabolic diseases, grant No. 92357305, 2024-2026, key member of project.
Youth Project of National Natural Science Foundation of China, Novel mechanism of Akk bacterial gavage in regulating NLRP3 inflammasome to improve cognitive impairment induced by type 2 diabetes mellitus, grant No. 92357305, 2020-2023, Principal Investigator Peking University Clinical Medicine +X Youth Special Project, Mechanism of acetic acid to improve diabetes-induced cognitive impairment by regulating NLRP3 inflammasome through ubiquitination-mitophagy pathway, grant No. PKU2023LCXQ009, 2023, Principal Investigator.
Sub-projects of the key project by the Ministry of Science and Technology for “Stem Cell Research and Organ Repair”, Mechanisms of Maternal-Fetal Tolerance and Their Application in the Induction of Immune Tolerance in Stem Cell Transplantation, grant No. 2022YFA1103600, 2022-2027, key member of project. First Class Grant of Post-doctoral Project Fund, The effects and mechanism of D-ribosylation on cognitive decline in patients with type 2 diabetes mellitus, grant No. 2018M630048, 2018-2021, Principal Investigator.
Youth project of Beijing Municipal Natural Science Foundation, The role and mechanism of short-chain fatty acids, metabolites of gut microbiota, in cognitive impairment induced by type 2 diabetes mellitus, grant No.7194284, 2019-2020, Principal Investigator. |
Selected publication:
Chunyou Mao#*, Mengru Gao#, Shaokun Zang#, Yanqing Zhu#, Dandan Shen, Linan Chen, Liu Yang, Zhiwei Wang, Huibing Zhang, Weiwei Wang, Qingya Shen, Yanhui Lu*, Xin Ma*, Yan Zhang*. Orthosteric and allosteric modulation of human HCAR2 signaling complex. Nature Communications. 2023;14(1), 7620.
Jie Zheng#, Yu An#, Yage Du, Ying Song, Qian Zhao, Yanhui Lu*. Effects of short-chain fatty acids on blood glucose and lipid levels in mouse models of diabetes mellitus: a systematic review and network meta-analysis. Pharmacological Research. 2024; 199:107041. Limin Cao#, Yu An#, Huiyuan Liu, Jinguo Jiang, Wenqi Liu, Yuhan Zhou, Mengyuan Shi, Wei Dai, Yanling Lv, Yuhong Zhao, Yanhui Lu*, Liangkai Chen*, Yang Xia*. Global epidemiology of type 2 diabetes in patients with NAFLD or MAFLD: a systematic review and meta-analysis. BMC Medicine. 2024, 22(1):101.
Yanhui Lu, Hua Jiang, Huijing Zhang, Ruxue Li, Qi Zhang, Dan Luo, Xue Cai, Mingzi Li*. Serum oxidized low density lipoprotein serves as a mediator for the inverse relationship between serum D-ribose and cognitive performance in type 2 diabetic patients. Free Radical Biology and Medicine. 2021; 171:91-98. Xin Zhang#, Tianzhi Xie#, Shuang Zhou#, Yingxuan Yuan, Weixuan Chen, Jie Zheng, Xuebo Liu, Tian Yuan*, Yanhui Lu*, Zhigang Liu*. Effects of the ApoE genotype on cognitive function in aging mice fed with a high-fat diet and the protective potential of n-3 polyunsaturated fatty acids. Food & Function. 2024; 15(4):2249-226.
Ying Song#, Fangxiao Cheng#, Yage Du, Jie Zheng, Yu An, Yanhui Lu*. Higher adherence to the AMED, DASH, and CHFP dietary patterns is associated with better cognition among Chinese middle-aged and elderly adults. Nutrients. 2023; 15(18): 3974. Zhaoming Cao, Yu An, Yanhui Lu*. Altered N6-methyladenosine modification patterns and transcript profiles contributes to cognitive dysfunction in high-fat induced diabetic mice. International Journal of Molecular Sciences. 2024, 25(4): 1990, 1990.
Yage Du, Xiaoying Li, Yu An, Ying Song, Yanhui Lu*. Association of gut microbiota with sort-chain fatty acids and inflammatory cytokines in diabetic patients with cognitive impairment: A cross-sectional, non-controlled study. Frontiers in Nutrition. 2022; 9:930626.Ying Song#, Yage Du#, Yu An, Jie Zheng, Yanhui Lu*. A systematic review and meta-analysis of cognitive and behavioral tests in rodents treated with different doses of D-ribose. Frontiers in Aging Neuroscience. 2022; 14:1036315. Yage Du, Liuqing Yang, Yu An, Ying Song, Yanhui Lu*. Health-related quality of life and associated factors in elderly individuals with dyslipidemia in rural Northern China. Quality of Life Research. 2023; 32(12):3547-3555.
Yage Du#, Qi Zhang#, Xiaolan Zhang, Ying Song, Jie Zheng, Yu An*, Yanhui Lu*. Correlation between inflammatory biomarkers, cognitive function and glycemic and lipid profiles in patients with type 2 diabetes mellitus: A systematic review and meta-analysis. Clinical Biochemistry. 2023; 121-122:110683. Jie Zheng#, Fangxiao Cheng#, Yage Du, Ying Song, Zhaoming Cao, Mingzi Li, Yanhui Lu*. Metabolic signatures and potential biomarkers in the progression of type 2 diabetes mellitus with cognitive impairment patients: A cross-sectional study. Interdisciplinary Nursing Research. 2023 February 2(1):p 19-26.
Yanhui Lu, Pengbo Xing, Xue Cai, Dan Luo, Ruxue Li, Cathy Lloyd, Norman Sartorius, Mingzi Li*. Prevalence and risk factors for diabetic peripheral neuropathy in type 2 diabetes in 14 countries: the INTERPRET-DD study. Frontiers in Public Health. 2020; 8:534372. Yanhui Lu, Xinjun Jiang,Shuling Liu, Mingzi Li*. Changes in cerebrospinal fluid Tau and β-Amyloid levels in diabetic and prediabetic patients: a meta-analysis. Frontiers in Aging Neuroscience. 2018; 10:271.
Yanhui Lu, Yu An, Jin Guo, Xiaona Zhang, Hui Wang, Hongguo Rong, Rong Xiao*. Dietary intake of nutrients and lifestyle affect the risk of mild cognitive impairment in the Chinese elderly population: a cross-sectional study. Frontiers in Behavioural Neuroscience. 2016; 10:229. Yanhui Lu, Yu An, Huanling Yu, Fengyuan Che, Xiaona Zhang, Hongguo Rong, Rong Xiao*. Sex-specific nonlinear associations between serum lipids and different domains of cognitive function in middle to older age individuals. Metabolic Brain Disease. 2017;32(4):1089-1097.
Yanhui Lu, Yu An, Chenyan Lv, Weiwei Ma, Yuandi Xi, Rong Xiao*. Dietary soybean isoflavones in Alzheimer’s disease prevention. Asia Pacific Journal of Clinical Nutrition. 2018;27(5):946-954. |
